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Table 4 Comparison of various studies with present study on risk factors of chronic liver disease

From: Risk factors for chronic liver disease in population of Central India: a case-control study from rural India

  Kudava et al. [15] Mishra et al. [16] Frieden et al. [18] Chen et al. [24] Singh et al. [25] Tellez-Avila et al. [26] Stepanova et al. [27] Zhang et al. [19] Madan et al. [29] Our study
Type of the study Retrospective Retrospective Case control Cross-sectional Retrospective Retrospective Retrospective Prospective Cross-sectional Case control
Year 1990 2009 1999 2006 2010 2008 2010 2011 2006 2009-2010
No. of participants 80 74 52 cases, 104 controls 371 60 134 964 4072 51 200 cases, 200 controls
Age (years)      35.1 ± 8 57 47 ± 11.2 49 ± 11.1 34 51.1 ± 12.1
Male: Female ratio      4:1 1:1.6 1:1.6 1:1.8 9.2:1 1:4.2
BMI      25.2 ± 3.6 27 ± 4.6 36.1 ± 9.1 27.2 ± 5.3 26.7 22.7 ± 4.2
BMI > 30 kg/m2      NA 16.8% NA 19.6% NA 1.9%
DM      8.33% 40% 28.1% 10% NA 21.1%
Hypertension      NA 29.1% 44% NA NA 25%
Alcohol 36% 60.8% 29% 0.8%       69%
Alcohol + Hepatitis B NA NA 6% 28.5%       3%
Alcohol + Hepatitis C NA NA 46% 13.2%       1%
Hepatitis C NA 6.7% 6% NA       0.5%
Hepatitis B 33% 8.1 NA NA       3.5%
NAFLD 34% 13.5% NA 33.6%       26%
RBS      NA NA 108 ± 29 NA 90 124 ± 56.1
ALT (IU/L)      110.82 ± 40.99 52.5 ± 39 58.5 ± 52.8 NA 98 54.31 ± 31.7
AST (IU/L)      70.6 ± 23.67 67.1 ± 60 42.4 ± 33.9 NA 66 95.46 ± 43.0
AST:ALT ratio      0.7 ± 0.3 NA NA NA NA 2.2 ± 1.1
Triglycerides (mg/dl)      NA 92.4 ± 49 167 ± 107 NA 145 87.5 ± 38.8
Total cholesterol (mg/dl)      NA NA 191 ± 45 NA 180 131.7 ± 39.1
LDL (mg/dl)      NA NA 108.6 ± 40 NA NA 56.8 ± 32.2
HDL (mg/dl)      NA 43.4 ± 10.9 47.1 ± 13.8 NA 41 45.9 ± 16.6