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Table 4 Three models of logistic multi regression analysis used to predict the most sensitive predictors of liver fibrosis

From: Growth differentiation factor 15: an emerging diagnostic biomarker of liver fibrosis in chronic hepatitis C patients

Module

Module 1

Module 2

Module 3

Item

Reg. Coef.

t

p

Sig.

Reg. Coef.

t

p

Sig.

Reg. Coef.

t

p

Sig.

Platelets (10^3/ul)

− 0.003

− 1.605

0.126

NS

− 0.003

− 2.55

0.01

S

− 0.002

− 1.66

0.014

S

GDF-15 (ng/L)

0

− 0.463

0.649

NS

0.001

2.112

0.04

S

0.001

2.002

0.05

S

Weight (kg)

− 0.023

− 2.201

0.041

S

0.006

0.828

0.41

NS

    

Prothrombin time (s)

0.21

1.609

0.125

NS

0.065

0.705

0.48

NS

INR

− 2.712

− 1.917

0.071

NS

0.474

0.43

0.67

NS

Age (years)

− 0.002

− 0.204

0.841

NS

    

Height (cm)

0.016

0.885

0.388

NS

AST (IU/L)

0.006

0.862

0.4

NS

ALT (IU/L)

0.003

0.468

0.645

NS

Bilirubin (mg/dl)

0.2

0.041

0.968

NS

Direct bilirubin (mg/dl)

0.238

0.049

0.962

NS

Indirect bilirubin (mg/dl)

0.431

0.089

0.93

NS

Albumin (g/L)

− 0.017

− 0.065

0.949

NS

Creatinine (mg/dl)

0.01

0.101

0.921

NS

Fasting blood sugar (mg/dl)

− 0.003

− 0.818

0.424

NS

Alfa fetoprotein (IU/ml)

0.016

0.803

0.433

NS

F ratio

2.16

2.984

6.003

p

0.059

0.02

0.005

Sig.

Not significant

Significant

Highly significant

  1. p > 0.05 is non-significant; p < 0.05: significant; p < 0.001 highly significant