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Table 4 Three models of logistic multi regression analysis used to predict the most sensitive predictors of liver fibrosis

From: Growth differentiation factor 15: an emerging diagnostic biomarker of liver fibrosis in chronic hepatitis C patients

Module Module 1 Module 2 Module 3
Item Reg. Coef. t p Sig. Reg. Coef. t p Sig. Reg. Coef. t p Sig.
Platelets (10^3/ul) − 0.003 − 1.605 0.126 NS − 0.003 − 2.55 0.01 S − 0.002 − 1.66 0.014 S
GDF-15 (ng/L) 0 − 0.463 0.649 NS 0.001 2.112 0.04 S 0.001 2.002 0.05 S
Weight (kg) − 0.023 − 2.201 0.041 S 0.006 0.828 0.41 NS     
Prothrombin time (s) 0.21 1.609 0.125 NS 0.065 0.705 0.48 NS
INR − 2.712 − 1.917 0.071 NS 0.474 0.43 0.67 NS
Age (years) − 0.002 − 0.204 0.841 NS     
Height (cm) 0.016 0.885 0.388 NS
AST (IU/L) 0.006 0.862 0.4 NS
ALT (IU/L) 0.003 0.468 0.645 NS
Bilirubin (mg/dl) 0.2 0.041 0.968 NS
Direct bilirubin (mg/dl) 0.238 0.049 0.962 NS
Indirect bilirubin (mg/dl) 0.431 0.089 0.93 NS
Albumin (g/L) − 0.017 − 0.065 0.949 NS
Creatinine (mg/dl) 0.01 0.101 0.921 NS
Fasting blood sugar (mg/dl) − 0.003 − 0.818 0.424 NS
Alfa fetoprotein (IU/ml) 0.016 0.803 0.433 NS
F ratio 2.16 2.984 6.003
p 0.059 0.02 0.005
Sig. Not significant Significant Highly significant
  1. p > 0.05 is non-significant; p < 0.05: significant; p < 0.001 highly significant