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Table 3 Comparative statistics of GDF-15 between control group and whole patients’ group and between each two patients’ sub-groups using Wilcoxon’s rank sum test

From: Growth differentiation factor 15: an emerging diagnostic biomarker of liver fibrosis in chronic hepatitis C patients

Group Control (n = 30) Patient group (n = 55) Wilcoxon rank sum test
Parameter Median Q1–Q3٭ Median Q1–Q3٭ Z p value
GDF-15 (ng/L) 110 100–120 410 300–530 − 7.442 0
Group Control (n = 30) Patient subgroup I (n = 18) Wilcoxon rank sum test
Parameter Median Q1–Q3٭ Median Q1–Q3٭ Z p value
GDF-15 (ng/L) 110 100–120 340 220–500 − 5.753 0
Group Subgroup І F0–F1 (n = 18) Subgroup II F2 (n = 13) Wilcoxon rank sum test
Parameter Median Q1–Q3٭ Median Q1–Q3٭ Z p value
GDF-15 (ng/L) 340 220–500 500 405–510 − 1.834 0.067
Group Subgroup І
F0–F1 (n = 18)
Subgroup III
F3–F4 (n = 24)
Wilcoxon rank sum test
Parameter Median Q1–Q3٭ Median Q1–Q3٭ Z p value
GDF-15 (ng/L) 340 220–500 415 335–587.5 − 2.065 0.039
Group Subgroup II
F2 (n = 13)
Subgroup III
F3–F4 (n = 24)
Wilcoxon rank sum test
Parameter Median Q1–Q3٭ Median Q1–Q3٭ Z p value
GDF-15 (ng/L) 500 405–510 415 335–587.5 − 0.08 0.936
  1. Q1–Q3* = Interquartile range (25th–75th percentiles) p value > 0.05 is non-significant, p value < 0.01 is highly significant