|
Parameter
|
Liver fibrosis patient group (n = 55)
|
Kruskal-Wallis test
|
|---|
|
Subgroup І F0-F1
|
Subgroup II F2
|
Subgroup III F3–F4
|
H
|
p value
|
|---|
|
n.
|
Median
|
Q1–Q3
|
n.
|
Median
|
Q1–Q3
|
n.
|
Median
|
Q1–Q3
|
|---|
|
Age (years)
|
16
|
32
|
28–47.25
|
12
|
37.5
|
32–47.5
|
22
|
52.5
|
43.75–57.5
|
12.522
|
0.002
|
|
Weight (kg)
|
18
|
73.5
|
68–78.25
|
13
|
75
|
67.5–86.5
|
24
|
70
|
66.5–84.5
|
0.273
|
0.873
|
|
AST (IU/L)
|
18
|
28
|
21–36.25
|
13
|
25
|
19–43
|
24
|
50.5
|
8.75–72.5
|
20.873
|
0
|
|
ALT (IU/L)
|
18
|
27
|
20.25–43.5
|
13
|
35
|
21.5–48
|
24
|
47
|
35.5–64.25
|
9.367
|
0.009
|
|
T. bilirubin (mg/dl)
|
18
|
0.65
|
0.475–0.8
|
13
|
0.6
|
0.35–0.8
|
24
|
1
|
0.8–1.75
|
16.122
|
0
|
|
D. bilirubin (mg/dl)
|
18
|
0.2
|
0.1–0.2
|
13
|
0.2
|
0.1–0.3
|
24
|
0.3
|
0.2–0.7
|
13.276
|
0.001
|
|
Albumin (g/L)
|
17
|
4.1
|
3.95–4.45
|
13
|
4.2
|
4–4.5
|
24
|
3.55
|
3.2–4.1
|
14.857
|
0.001
|
|
Platelets (10^3/ul)
|
18
|
232
|
188.25–256
|
13
|
256
|
219–295.5
|
24
|
135
|
91–223.75
|
15.835
|
0
|
|
INR
|
18
|
1
|
0.987–1.025
|
13
|
1
|
1–1.1
|
23
|
1.1
|
1–1.3
|
10.895
|
0.004
|
|
AFP (IU/ml)
|
9
|
2.5
|
1.2–5.45
|
11
|
2.9
|
1.9–4.5
|
23
|
9.2
|
2.9–13.6
|
9.89
|
0.007
|
|
GDF-15 (ng/L)
|
18
|
340
|
220–500
|
13
|
500
|
405–510
|
24
|
415
|
335–587.5
|
5.185
|
0.075
|
- Q1–Q3* = interquartile range (25th–75th percentiles); p value > 0.05 is non-significant; p value < 0.01 is highly significant
