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Table 1 Comparison of the baseline parameters in both groups

From: High efficacy of low-dose albumin infusion in the prevention of paracentesis-induced circulatory dysfunction

 Low-dose albuminStandard-dose albuminp
N = 85N = 25
Age (years)53.19 ± 8.5551.60 ± 6.840.397
SexMale50 (58.8%)9 (36%)0.067
Female35 (41.2%)16 (64%)
EtiologyHCV80 (93%)22 (91.7%)1
Non-HCV6 (7%)2 (8.3%)
Child Pugh classChild B73 (85.9%)13 (52%)0.001
Child C12 (14.1%)12 (48%)
PICDNone64 (75.3%)22 (88%)0.27
PICD21 (24.7%)3 (12%)
Weight, kg90.56 ± 11.2687.08 ± 14.180.252
MAP, mmHg78.98 ± 6.4077.58 ± 5.810.358
Heart rate, beat/minute83.70 ± 13.7383.12 ± 5.240.84
Paracentesis, L9.78 ± 3.5612.52 ± 3.600.001
Total bilirubin, mg/dL3.04 ± 2.652.78 ± 1.590.643
Total protein, g/dL6.38 ± 0.936.33 ± 1.210.836
Albumin, g/dL2.20 ± 0.362.55 ± 0.600.002#
AST, U/L53.48 ± 26.7872.32 ± 48.920.106#
ALT, U/L35.48 ± 27.8035.84 ± 24.110.954
ALP, U/L104.21 ± 132.88119.24 ± 103.150.604
GGT, U/L47.66 ± 46.1152.95 ± 68.150.66
Hemoglobin, g/dL10.36 ± 1.3210.12 ± 1.980.319#
WBCs, 109/L6.90 ± 9.274.98 ± 2.550.309
Platelets, 109/L82.14 ± 33.3283.60 ± 38.470.853
INR1.62 ± 0.511.55 ± 0.280.495
Urea, mg/dL55.35 ± 30.4838.16 ± 17.070.003#
Creatinine, mg/dL0.95 ± 0.270.85 ± 0.360.103#
Sodium, mmol/L123.25 ± 13.85128.16 ± 6.030.088
Potassium, mmol/L4.28 ± 0.694.20 ± 0.580.636
Child Pugh score10.36 ± 1.269.88 ± 1.560.113
MELD15.24 ± 4.4115.28 ± 4.110.964
MELD Na22.88 ± 4.1221.88 ± 4.020.285
PRA, pg/mL859.62 ± 1151.34165.93 ± 95.340.001#
  1. PICD paracentesis-induced circulatory dysfunction, MAP mean arterial pressure, PRA plasma renin activity, HCV hepatitis C virus, MELD model for end-stage liver disease
  2. #Mann–Whitney U test