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Table 1 Demographic, clinical, and laboratory data of the studied groups

From: A novel serum index for accurate diagnosis of spontaneous bacterial peritonitis in cirrhotic patients without other infections

  Sterile ascites n = 118 SBP n = 60 P
Age (mean ± SD, years) 57.3 ± 7.3 57.6 ± 6.8 0.824
Male sex 55 (46.6%) 38 (63.3%) 0.073
Hypertension 12 (10.2%) 9 (15.0%) 0.345
Diabetes mellitus 18 (15.3%) 11 (18.3%) 0.599
Cause of liver disease 0.727**
 - HCV infection 94 (79.7%) 51 (85.5%)
 - HBV infection 20 (16.9%) 8 (13.3%)
 - Other causes 4 (3.4%) 1 (1.7%)
Serum albumin (mean ± SD, g/dL) 2.53 ± 0.18 2.49 ± 0.21 0.178
Serum Total bilirubin (median/IQR, mg/dL) 2.11/0.91–3.29 2.00/1.50–3.42 0.167*
INR (mean ± SD) 1.47 ± 0.20 1.53 ± 0.28 0.095
ALT (median/IQR, IU/L) 27/18–38 34/15–44 0.387*
AST (median/IQR, IU/L) 48/36–60 47/29–74 0.892*
Serum creatinine (median/IQR, mg/dL) 1.00/1.00–1.00 1.00/1.00–1.75 0.158*
Serum LDH (mean ± SD, IU/L) 214 ± 54 226 ± 51 0.126
Blood TLC (median/IQR, × 103/mm3) 6.10/4.00–8.00 7.00/4.43–8.90 0.158*
Hemoglobin (mean ± SD, g/dL) 10.07 ± 1.49 10.06 ± 1.33 0.952
Platelets count (median/IQR, × 103/mm3) 90/66–144 82/66–144 0.550*
ESR (median/IQR, mm/hour) 25/19–30 31/23–36 < 0.001*
CRP (median/IQR, mg/L) 20/11–25 27/24–29 < 0.001*
PCT (median/IQR, ng/mL) 0.259/0.159–0.350 0.691/0.604–1.690 < 0.001*
PEC index [PCT × (ESR + CRP)] (median/IQR) 9.89/5.93–15.00 41.04/31.18–92.99 < 0.001*
Ascitic fluid albumin (mean ± SD, g/dL) 0.837 ± 0.148 0.875 ± 0.128 0.094
Ascitic fluid glucose (mean ± SD, g/dL) 112 ± 17 99 ± 12 < 0.001
Ascitic fluid LDH (mean ± SD, IU/L) 109 ± 18 157 ± 42 < 0.001
Ascitic fluid PMNL (median/IQR, cell/mm3) 200/170–207 3334/274–641 < 0.001*
Ascitic fluid PMNL ≥ 250/mm3 0 (0.0%) 60 (100.0%) < 0.001
Positive ascitic fluid bacterial culture 0 (0.0%) 25 (41.7%) < 0.001
  1. SD standard deviation, IQR interquartile range, HCV hepatitis C virus, HBV hepatitis B virus, INR international normalized ratio, ALT alanine aminotransferase, AST aspartate aminotransferase, IU international unit, LDH lactate dehydrogenase, TLC total leukocytic count, ESR erythrocyte sedimentation rate, CRP C-reactive protein, PCT procalcitonin, PMNL polymorphonuclear leukocytes
  2. *Mann–Whitney U test, ** Fisher’s exact test