Skip to main content
Egyptian Liver Journal

Table 5 Comparison between the four studied groups according to genotype distribution of IRS1 G972R (rs 1801278) polymorphism

From: Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus

Parameters

Group I (n = 50)

Group II (n = 50)

Group III (n = 52)

Group IV (n = 50)

χ2

P

N

%

N

%

N

%

N

%

IRS1 G972R

 GG Homo wild

35

70.0

23

46.0

24

46.2

21

42.0

12.243*

MCP = 0.034*

 GA Hetero

15

30.0

23

46.0

26

50.0

27

54.0

 AA Homo mutant

0

0.0

4

8.0

2

3.8

2

4.0

  Sig. bet. Grps

MCP1 = 0.017*, MCP2 = 0.019*, MCP3 = 0.009*, MCP4 = 0.700, MCP5 = 0.627, MCP6 = 0.880

  

 G

85

85.0

69

69.0

72

69.2

74

74.0

8.861*

0.031*

 A

15

15.0

31

31.0

32

30.8

26

26.0

  Sig. bet. Grps

P1 = 0.007*, P2 = 0.017*, P3 = 0.007, P4 = 0.972, P5 = 0.434, P6 = 0.450

  
  1. χ2 chi-square test, MC Monte Carlo, P P value for comparing between the different groups, common letters are not significant (i.e., different letters are significant), P1 P value for comparing between group I and group II, P2 P value for comparing between group I and group III, P3 P value for comparing between group I and group IV, P4 P value for comparing between group II and group III, P5 P value for comparing between group II and group IV, P6 P value for comparing between group III and group IV, Sig. bet. Grps significance between groups
  2. *Statistically significant at P ≤ 0.05
Back to article page