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Table 3 Statistical significance of serum urea, creatinine, and uric acid in the studied groups

From: Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus

Parameters Group I (n = 50) Group II (n = 50) Group III (n = 52) Group IV (n = 50) Test of sig. P
Urea (mg/dl)
 Min.–Max. 12.0–40.0 20.0–99.0 11.0–250.0 14.0–242.0 H = 41.355 < 0.001*
 Mean ± SD. 26.32 ± 7.05 40.82 ± 20.38 47.58 ± 44.06 59.56 ± 43.55
 Median 26.0 34.0 35.0 45.0
PGroup I   < 0.001* < 0.001* < 0.001*   
Sig. bet. Groups   P1 = 0.829, P2 = 0.028*, P3 = 0.045*   
Creatinine (mg/dl)
 Min.–Max. 0.60–1.10 0.70–2.10 0.60–4.80 0.60–2.50 H = 50.629 < 0.001*
 Mean ± SD. 0.81 ± .15 1.08 ± 0.38 1.25 ± 0.64 1.21 ± 0.42
 Median 0.80 0 .90 1.10 1.15
PGroup I   < 0.001* < 0.001* < 0.001*   
Sig. bet. Groups   P1 = 0.031*, P2 = 0.031*, P3 = 0.983   
Uric acid (mg/dl)
 Min.–Max. 2.90–5.80 3.80–10.0 2.10–6.70 3.50–9.30 F = 44.584 <0.001*
 Mean ± SD. 4.33 ± .76 6.72 ± 1.74 4.17 ± 1.01 5.67 ± 1.40
 Median 4.30 6.50 4.10 5.30
PGroup I   < 0.001* 0.916 < 0.001*   
Sig. bet. Groups   P1 < 0.001*, P2 < 0.001*, P3 < 0.001*   
  1. F, F for ANOVA test, pairwise comparison bet. each 2 groups was done using post hoc test (Tukey); H, H for Kruskal–Wallis test, pairwise comparison bet. each 2 groups was done using post hoc test (Dunn’s for multiple comparisons test); P, P value for comparing between the different groups; PGroup I, P value for comparing between group I and each other groups; P1, P value for comparing between group II and group III; P2, P value for comparing between group II and group IV; P3, P value for comparing between group III and group IV; Sig. bet. Groups, significance between groups
  2. *Statistically significant at P ≤ 0.05