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Table 7 Insulin resistance (assessed by HOMA-IR and QUICKI index) and genotypes of IRS-1 SNP in relation to the degree of liver cirrhosis (assessed by Child–Pugh classification) in group IV

From: Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus

 

Child class A

Child class B

Child class C

Test of sig.

P

HOMA-IR

 Min.–Max.

4.60-29.60

5.10-27.50

5.00-65.10

F = 8.689

0.001

 Mean ± SD.

8.867 ± 8.384

9.904 ± 5.418

22.833 ± 16.102

QUICKI index

 Min.–Max.

0.25-0.31

0.21-0.30

0.23-0.30

F = 6.668

0.003

 Mean ± SD.

0.291 ± 0.020

0.280 ± 0.022

0.260 ± 0.021

Genotype

 GG

8

8

5

X2 = 5.173

0.270

 GA

4

17

6

 AA

0

1

1