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Table 7 Insulin resistance (assessed by HOMA-IR and QUICKI index) and genotypes of IRS-1 SNP in relation to the degree of liver cirrhosis (assessed by Child–Pugh classification) in group IV

From: Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus

  Child class A Child class B Child class C Test of sig. P
HOMA-IR
Min.–Max. 4.60-29.60 5.10-27.50 5.00-65.10 F = 8.689 0.001
Mean ± SD. 8.867 ± 8.384 9.904 ± 5.418 22.833 ± 16.102
QUICKI index
Min.–Max. 0.25-0.31 0.21-0.30 0.23-0.30 F = 6.668 0.003
Mean ± SD. 0.291 ± 0.020 0.280 ± 0.022 0.260 ± 0.021
Genotype
GG 8 8 5 X2 = 5.173 0.270
GA 4 17 6
AA 0 1 1