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Table 4 Relationship between the individual ApaI genotypes and severity of liver disease among the two groups

From: Vitamin D receptor gene polymorphisms and risk of hepatocellular carcinoma in hepatitis C-related liver cirrhosis

Parameter ApaI genotype P value
HCC− group   CC (n = 6) CA (n = 12) AA (n = 10)  
Child class
A 0 (0.0%) 1 (8.3%) 3 (30%) 0.011
B 0 (0.0%) 4 (33.3%) 6 (60%)
C 6 (100%) 7 (58.4%) 1 (10%)
MELD score
Mean ± SD 20.33 ± 1.37 17.92 ± 4.85 13.4 ± 4.69 0.01
Median (range) 20.5 (18–22) 17.5 (9–25) 12.5 (8–21)
HCC+ group   CC (n = 38) CA (n = 7) AA (n = 3)  
Child class
A 4 (10.5%) 4 (57.1%) 0 (0.0%) 0.003
B 14 (36.9%) 3 (42.9%) 3 (100%)
C 20 (52.6%) 0 (0.0%) 0 (0.0%)
MELD score
Mean ± SD 17.37 ± 4.92 9.57 ± 3.26 14 ± 2.65 0.001
Median (range) 17 (8–31) 8 (6–16) 15 (11–16)