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Table 4 Relationship between the individual ApaI genotypes and severity of liver disease among the two groups

From: Vitamin D receptor gene polymorphisms and risk of hepatocellular carcinoma in hepatitis C-related liver cirrhosis

Parameter

ApaI genotype

P value

HCC− group

 

CC (n = 6)

CA (n = 12)

AA (n = 10)

 

Child class

A

0 (0.0%)

1 (8.3%)

3 (30%)

0.011

B

0 (0.0%)

4 (33.3%)

6 (60%)

C

6 (100%)

7 (58.4%)

1 (10%)

MELD score

Mean ± SD

20.33 ± 1.37

17.92 ± 4.85

13.4 ± 4.69

0.01

Median (range)

20.5 (18–22)

17.5 (9–25)

12.5 (8–21)

HCC+ group

 

CC (n = 38)

CA (n = 7)

AA (n = 3)

 

Child class

A

4 (10.5%)

4 (57.1%)

0 (0.0%)

0.003

B

14 (36.9%)

3 (42.9%)

3 (100%)

C

20 (52.6%)

0 (0.0%)

0 (0.0%)

MELD score

Mean ± SD

17.37 ± 4.92

9.57 ± 3.26

14 ± 2.65

0.001

Median (range)

17 (8–31)

8 (6–16)

15 (11–16)