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Table 2 Statistical significance of fasting serum glucose level (FSG) (mg/dl), postprandial serum glucose (PPSG) (mg/dl), HbA1C (%), fasting insulin (μIU/ml), and HOMA-IR and QUICKI index in the studied groups

From: Could insulin receptor H1085H C > T single nucleotide polymorphism predict insulin resistance in type 2 diabetic and chronic hepatitis C virus patients in Egypt?

  Group I (n = 50) Group II (n = 50) Group III (n = 52) Group IV (n = 50) Test of sig. P
FSG (mg/dl)
 Min.–Max. 75.0–99.0 129.0–322.0 59.0–100.0 83.0–766.0 H = 143.378 < 0.001*
 Mean ± SD 86.3 ± 5.62 195.2 ± 51.82 82.31 ± 11.46 182.68 ± 106.6
 Median 87.0 189.0 80.0 168.50
pGroup I   < 0.001* 0.239 <0.001*   
Sig. bet. Grps   p1 < 0.001*, p2 = 0.132, p3 < 0.001*   
PPSG (mg/dl)
 Min.–Max. 85.0–130.0 108.0–391.0 77.0–145.0 85.0–540.0 F = 72.836 < 0.001*
 Mean ± SD 102.3 ± 12.9 207.3 ± 70.44 101.6 ± 17.87 223.62 ± 81.85
 Median 99.0 201.0 95.0 210.0
pGroup I   < 0.001* 1.000 < 0.001*   
Sig. bet. Grps   p1 < 0.001*, p2 = 0.447, p3 < 0.001*   
HbA1C (%)
 Min.–Max. 3.80–5.50 6.20–13.70 3.80–5.40 5.40–12.20 F = 145.963 < 0.001*
 Mean ± SD 4.68 ± 0.49 8.75 ± 2.01 4.58 ± 0.47 7.89 ± 1.42
 Median 4.80 8.10 4.50 7.75
pGroup I   < 0.001* 0.974 < 0.001*   
Sig. bet. Grps   p1 < 0.001*, p2 = 0.005*, p3 < 0.001*   
Fasting insulin (μIU/ml)
 Min.–Max. 1.20–10.10 5.40–77.0 2.40–25.30 10.0–514.2 H = 121.986 < 0.001*
 Mean ± SD 5.75 ± 2.65 17.09 ± 16.22 9.19 ± 3.65 40.68 ± 72.89
 Median 5.65 11.0 9.30 18.65
pGroup I   < 0.001* < 0.001* < 0.001*   
Sig. bet. Grps   p1 = 0.002*, p2 < 0.001*, p3 < 0.001*   
HOMA-IR
 Min.–Max. 0.30–2.20 2.70–49.0 0.50–5.30 4.60–65.10 H = 157.864 < 0.001*
 Mean ± SD 1.23 ± 0.55 9.14 ± 11.09 1.81 ± 0.73 12.76 ± 11.04
 Median 1.30 5.10 1.95 7.40
pGroup I   < 0.001* 0.019* < 0.001*   
Sig. bet. Grps   p1 < 0.001*, p2 = 0.055, p3 < 0.001*   
QUICKI index
 Min.–Max. 0.34–0.49 0.23–0.33 0.30–0.43 0.21–0.31 F = 150.524 < 0.001*
 Mean ± SD 0.38 ± 0.04 0.30 ± 0.03 0.35 ± 0.02 0.28 ± 0.02
 Median 0.37 0.30 0.35 0.29
pGroup I   < 0.001* < 0.001* < 0.001*   
Sig. bet. Grps   p1 < 0.001*, p2 = 0.009*, p3 < 0.001*