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Table 2 Statistical significance of fasting serum glucose level (FSG) (mg/dl), postprandial serum glucose (PPSG) (mg/dl), HbA1C (%), fasting insulin (μIU/ml), and HOMA-IR and QUICKI index in the studied groups

From: Could insulin receptor H1085H C > T single nucleotide polymorphism predict insulin resistance in type 2 diabetic and chronic hepatitis C virus patients in Egypt?

 

Group I (n = 50)

Group II (n = 50)

Group III (n = 52)

Group IV (n = 50)

Test of sig.

P

FSG (mg/dl)

 Min.–Max.

75.0–99.0

129.0–322.0

59.0–100.0

83.0–766.0

H = 143.378

< 0.001*

 Mean ± SD

86.3 ± 5.62

195.2 ± 51.82

82.31 ± 11.46

182.68 ± 106.6

 Median

87.0

189.0

80.0

168.50

pGroup I

 

< 0.001*

0.239

<0.001*

  

Sig. bet. Grps

 

p1 < 0.001*, p2 = 0.132, p3 < 0.001*

  

PPSG (mg/dl)

 Min.–Max.

85.0–130.0

108.0–391.0

77.0–145.0

85.0–540.0

F = 72.836

< 0.001*

 Mean ± SD

102.3 ± 12.9

207.3 ± 70.44

101.6 ± 17.87

223.62 ± 81.85

 Median

99.0

201.0

95.0

210.0

pGroup I

 

< 0.001*

1.000

< 0.001*

  

Sig. bet. Grps

 

p1 < 0.001*, p2 = 0.447, p3 < 0.001*

  

HbA1C (%)

 Min.–Max.

3.80–5.50

6.20–13.70

3.80–5.40

5.40–12.20

F = 145.963

< 0.001*

 Mean ± SD

4.68 ± 0.49

8.75 ± 2.01

4.58 ± 0.47

7.89 ± 1.42

 Median

4.80

8.10

4.50

7.75

pGroup I

 

< 0.001*

0.974

< 0.001*

  

Sig. bet. Grps

 

p1 < 0.001*, p2 = 0.005*, p3 < 0.001*

  

Fasting insulin (μIU/ml)

 Min.–Max.

1.20–10.10

5.40–77.0

2.40–25.30

10.0–514.2

H = 121.986

< 0.001*

 Mean ± SD

5.75 ± 2.65

17.09 ± 16.22

9.19 ± 3.65

40.68 ± 72.89

 Median

5.65

11.0

9.30

18.65

pGroup I

 

< 0.001*

< 0.001*

< 0.001*

  

Sig. bet. Grps

 

p1 = 0.002*, p2 < 0.001*, p3 < 0.001*

  

HOMA-IR

 Min.–Max.

0.30–2.20

2.70–49.0

0.50–5.30

4.60–65.10

H = 157.864

< 0.001*

 Mean ± SD

1.23 ± 0.55

9.14 ± 11.09

1.81 ± 0.73

12.76 ± 11.04

 Median

1.30

5.10

1.95

7.40

pGroup I

 

< 0.001*

0.019*

< 0.001*

  

Sig. bet. Grps

 

p1 < 0.001*, p2 = 0.055, p3 < 0.001*

  

QUICKI index

 Min.–Max.

0.34–0.49

0.23–0.33

0.30–0.43

0.21–0.31

F = 150.524

< 0.001*

 Mean ± SD

0.38 ± 0.04

0.30 ± 0.03

0.35 ± 0.02

0.28 ± 0.02

 Median

0.37

0.30

0.35

0.29

pGroup I

 

< 0.001*

< 0.001*

< 0.001*

  

Sig. bet. Grps

 

p1 < 0.001*, p2 = 0.009*, p3 < 0.001*