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Table 5 Comparison of different IL-18 genotypes in the studied groups

From: Interleukin-18 polymorphism as a diagnostic tumor marker for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis

 

Group

P value

Within-group significance

Control group (N = 20)

Cirrhosis group (N = 37)

HCC group (N = 33)

AA

4 (20%)

11 (29.7%)

9 (27.3%)

P = 0.727

p1 = 0.46

p2 = 0.56

p3 = 0.82

AC

12 (60%)

19 (51.4%)

18 (54.5%)

P = 0.822

p1 = 0.53

p2 = 0.69

p3 = 0.79

CC

4 (20%)

7 (18.9%)

6 (18.2%)

P = 0.972

p1 = 0.92

p2 = 0.92

p3 = 1.0

CC

0 (0.0)

1 (2.7)

1 (3.0)

P = 0.98

p1 = 1.0

p2 = 1.0

p3 = 1.0

GC

1 (5%)

8 (21.6%)

8 (24.2%)

P = 0.191

p1 = 0.10

p2 = 0.07

p3 = 0.79

GG

19 (95%)

28 (75.7%)

24 (72.7%)

P = 0.03*

p1 = 0.07

p2 = 0.04*

p3 = 0.78

  1. This table shows that there is only a statistically significant difference in the GG genotype in the HCC group in comparison with the control group (P = 0.04)
  2. p1 comparison of the control and cirrhosis groups, p2 comparison of control and HCC, p3 comparison of cirrhosis and HCC