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Table 5 Comparison of different IL-18 genotypes in the studied groups

From: Interleukin-18 polymorphism as a diagnostic tumor marker for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis

  Group P value Within-group significance
Control group (N = 20) Cirrhosis group (N = 37) HCC group (N = 33)
AA 4 (20%) 11 (29.7%) 9 (27.3%) P = 0.727 p1 = 0.46
p2 = 0.56
p3 = 0.82
AC 12 (60%) 19 (51.4%) 18 (54.5%) P = 0.822 p1 = 0.53
p2 = 0.69
p3 = 0.79
CC 4 (20%) 7 (18.9%) 6 (18.2%) P = 0.972 p1 = 0.92
p2 = 0.92
p3 = 1.0
CC 0 (0.0) 1 (2.7) 1 (3.0) P = 0.98 p1 = 1.0
p2 = 1.0
p3 = 1.0
GC 1 (5%) 8 (21.6%) 8 (24.2%) P = 0.191 p1 = 0.10
p2 = 0.07
p3 = 0.79
GG 19 (95%) 28 (75.7%) 24 (72.7%) P = 0.03* p1 = 0.07
p2 = 0.04*
p3 = 0.78
  1. This table shows that there is only a statistically significant difference in the GG genotype in the HCC group in comparison with the control group (P = 0.04)
  2. p1 comparison of the control and cirrhosis groups, p2 comparison of control and HCC, p3 comparison of cirrhosis and HCC