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Table 2 Comparison of laboratory findings in cirrhosis and HCC groups

From: Interleukin-18 polymorphism as a diagnostic tumor marker for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis

Variables

Cirrhosis group (N = 37)

HCC group (N = 33)

Test of significance

PCR (× 105)

11.08 ± 12.48

4.76 ± 2.89

P = 0.178

SGPT

39.73 ± 29.29

110.85 ± 69.11

P = 0.001*

SGOT

43.57 ± 24.76

133.61 ± 140.42

P < 0.001*

Albumin

4.11 ± 0.61

2.85 ± 0.72

P < 0.001*

Total bilirubin

1.06 ± 0.67

9.68 ± 10.81

P < 0.001*

Direct bilirubin

0.36 ± 0.33

6.67 ± 7.86

P < 0.001*

INR

1.19 ± 0.32

1.46 ± 0.37

P < 0.001*

Creatinine

0.79 ± 0.25

1.61 ± 1.49

P < 0.001*

Platelets

145.08 ± 59.88

122.64 ± 66.63

P = 0.062

Hgb

12.91 ± 1.94

11.41 ± 1.88

P = 0.002*

WBCs

5.51 ± 1.31

9.67 ± 9.56

P = 0.034*

  1. This table shows significantly higher SGPT, SGOT, total bilirubin, direct bilirubin, INR, creatinine (P < 0.001 for all), and WBCs (P < 0.034) in the HCC group and significantly lower albumin and Hgb in the HCC group (P < 0.001 and P = 0.002, respectively)
  2. *Statistically significant if P < 0.05