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Table 2 Comparison of laboratory findings in cirrhosis and HCC groups

From: Interleukin-18 polymorphism as a diagnostic tumor marker for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis

Variables Cirrhosis group (N = 37) HCC group (N = 33) Test of significance
PCR (× 105) 11.08 ± 12.48 4.76 ± 2.89 P = 0.178
SGPT 39.73 ± 29.29 110.85 ± 69.11 P = 0.001*
SGOT 43.57 ± 24.76 133.61 ± 140.42 P < 0.001*
Albumin 4.11 ± 0.61 2.85 ± 0.72 P < 0.001*
Total bilirubin 1.06 ± 0.67 9.68 ± 10.81 P < 0.001*
Direct bilirubin 0.36 ± 0.33 6.67 ± 7.86 P < 0.001*
INR 1.19 ± 0.32 1.46 ± 0.37 P < 0.001*
Creatinine 0.79 ± 0.25 1.61 ± 1.49 P < 0.001*
Platelets 145.08 ± 59.88 122.64 ± 66.63 P = 0.062
Hgb 12.91 ± 1.94 11.41 ± 1.88 P = 0.002*
WBCs 5.51 ± 1.31 9.67 ± 9.56 P = 0.034*
  1. This table shows significantly higher SGPT, SGOT, total bilirubin, direct bilirubin, INR, creatinine (P < 0.001 for all), and WBCs (P < 0.034) in the HCC group and significantly lower albumin and Hgb in the HCC group (P < 0.001 and P = 0.002, respectively)
  2. *Statistically significant if P < 0.05