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Table 3 Statistical comparison between pre-treatment and post-treatment parameters in glycemic improved patients

From: Effect of eradication of HCV infection by direct-acting antivirals in diabetic HCV-infected patients as regards glycemic control

 

Pre-treatment (no = 32)

Post-treatment (no = 32)

P value

Hemoglobin (g/dL)a

13.07 ± 1.05

12.57 ± 1.23

0.002

Leukocytes (× 103/μL cells)a

6.53 ± 1.91

6.58 ± 2.03

0.876

Platelets (× 103/μL cells)a

206.56 ± 53.82

217.31 ± 47.82

0.130

Albumin (g/dL)a

4.30 ± 0.40

4.31 ± 0.37

0.501

Bilirubin, total (mg/dL)a

0.78 ± 0.22

0.67 ± 0.19

0.009

INRa

1.41 ± 1.75

1.07 ± 0.09

0.290

AST (IU/L)a

51.59 ± 28.20

24.53 ± 8.27

0.001

ALT (IU/L)a

64.13 ± 35.90

24.22 ± 7.98

0.001

Creatinine (mg/dL)a

0.87 ± 0.15

0.88 ± 0.15

0.525

HbA1c (%)a

7.91 ± 0.69

6.50 ± 0.72

0.001

AFP (ng/mL)a

7.41 ± 6.24

6.56 ± 5.94

0.032

FIB-4b scorea

1.75 ± 0.76

1.17 ± 0.44

0.001

  1. aMean ± SD. Glycemic improved group: ≥ 1% reduction of baseline HbA1c levels at SVR. Non-glycemic improved group: < 1% reduction of baseline HbA1c levels at SVR
  2. AFP Alpha-fetoprotein, ALT Alanine transaminase, AST Aspartate transaminase, bFIB-4 score = [age 3AST]/[platelets 3 ALT1/2], INR international normalized ratio, HbA1c glycated hemoglobin