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Table 3 Serum ATX levels according to the fibrosis grade at baseline and SVR12

From: The impact of achieving a sustained virological response with direct-acting antivirals on serum autotaxin levels in chronic hepatitis C patients

 

F0–1

F2

F3

F4

p value

Serum ATX level (pg/mL), median (IQR)

Baseline

420 (371.25–595)

501 (444–547)

512 (390–1443)

549 (393.75–1552.25)

0.389a, 0.043b

SVR12

361.50 (334–445.75)

404.50 (322–489)

417.50 (371.50–1260.25)

451 (320–1275)

0.569a, 0.083b

p value

 

0.003

< 0.001

0.031

< 0.001

 
  1. ATX autotaxin, IQR interquartile range
  2. aKruskal-Wallis test
  3. bJonckheere-Terpstra test