The role of serum bile acid profile in differentiation between nonalcoholic fatty liver disease and chronic viral hepatitis

Egyptian Liver Journal

Table 5 Comparison between viral hepatitis and NAFLD groups according to the cutoff values of their bile acids

	Viral hepatitis (group II) (n = 146)		NAFLD (group III) (n = 39)		χ²	p
	No.	%	No.	%	χ²	p
TCA
≤ 0.001	67	45.9	36	92.3	26.872*	< 0.001*
> 0.001	79	54.1	3	7.7	26.872*	< 0.001*
TCDCA
≤ 0.02	57	39.0	22	56.4	3.795	0.051
> 0.02	89	61.0	17	43.6	3.795	0.051
TUDCA
≤ 0	59	40.4	17	43.6	0.128	0.720
> 0	87	59.6	22	56.4	0.128	0.720
TLCA
≤ 0	49	33.6	17	43.6	1.349	0.245
> 0	97	66.4	22	56.4	1.349	0.245
GCA
≤ 0.35	71	48.6	25	64.1	2.952	0.086
> 0.35	57	51.4	14	35.9	2.952	0.086
GCDCA
≤ 1.1	73	50.0	30	76.9	9.040*	0.003*
> 1.1	73	50.0	9	23.1	9.040*	0.003*
UDCA
≤ 0	36	24.7	20	51.3	10.337^*	0.001^*
> 0	110	75.3	19	48.7	10.337^*	0.001^*
DCA
≤ 0.04	27	18.5	17	43.6	10.694^*	0.001^*
> 0.04	119	81.5	22	56.4	10.694^*	0.001^*
LCA
≤ 0	61	41.8	36	92.3	31.505^*	< 0.001^*
> 0	85	58.2	3	7.7	31.505^*	< 0.001^*

χ² Chi-square test, p value for comparing between the studied groups
CDCA Chenodeoxycholic acid,TCA taurocholic acid, TCDCA taurochenodeoxycholic acid, TUDCA taurodeoxycholic acid, TLCA taurolithocholic acid, GCA glycholic acid, GCDCA, UDCA ursodeoxycholic acid, DCA deoxycholic acid, LCA lithocholic acid
*Statistically significant at p ≤ 0.05