| |
Control (n = 51)
|
Viral hepatitis (HBV + HCV) (n = 146)
|
NAFLD (n = 39)
|
Test of significance
|
p
|
Significance between groups
|
|---|
|
I vs. II
|
I vs. III
|
II vs. III
|
|---|
|
AST (IU/L)
|
|
Min.–Max.
|
10.0–44.0
|
10.0–143.0
|
13.0–55.0
|
H = 26.719
|
< 0.001*
|
< 0.001*
|
0.001*
|
0.498
|
|
Mean ± SD
|
20.70 ± 6.55
|
40.60 ± 32.16
|
29.28 ± 11.50
|
|
Median
|
19.0
|
28.0
|
27.0
|
|
ALT (IU/L)
|
|
Min.–Max.
|
10.0–39.0
|
9.0–181.0
|
11.0–64.0
|
H = 17.105*
|
< 0.001*
|
< 0.001*
|
< 0.001*
|
0.196
|
|
Mean ± SD.
|
20.25 ± 8.57
|
37.26 ± 35.63
|
31.90 ± 14.36
|
|
Median
|
18.0
|
24.50
|
31.0
|
|
ALB (g/dl)
|
|
Min.–Max.
|
4.0–4.80
|
1.40–5.50
|
2.80–4.80
|
F = 4.278*
|
0.015*
|
0.031*
|
0.024*
|
0.693
|
|
Mean ± SD.
|
4.42 ± 0.20
|
4.15 ± 0.78
|
4.06 ± 0.43
|
|
Median
|
4.40
|
4.40
|
4.13
|
|
TBIL (mg/dl)
|
|
Min.–Max.
|
0.23–1.27
|
0.20–7.30
|
0.23–1.20
|
H = 11.609*
|
0.003*
|
0.002*
|
0.499
|
0.042*
|
|
Mean ± SD.
|
0.51 ± 0.25
|
0.89 ± 1.10
|
0.52 ± 0.22
|
|
Median
|
0.40
|
0.56
|
0.50
|
|
DBIL (mg/dl)
|
|
Min.–Max.
|
0.10–0.70
|
0.10–6.10
|
0.10–0.70
|
H = 7.387*
|
0.025*
|
0.029*
|
0.922
|
0.037*
|
|
Mean ± SD.
|
0.23 ± 0.14
|
0.57 ± 1.08
|
0.22 ± 0.13
|
|
Median
|
0.20
|
0.23
|
0.20
|
|
GGT (IU/ml)
|
|
Min.–Max.
|
9.0–82.0
|
8.0–259.0
|
10.0–300.0
|
H = 25.195*
|
< 0.001*
|
< 0.001*
|
< 0.001*
|
0.969
|
|
Mean ± SD.
|
22.91 ± 13.56
|
45.97 ± 44.15
|
44.78 ± 47.08
|
|
Median
|
19.0
|
32.0
|
29.0
|
|
ALP(IU/ml)
|
|
Min.–Max.
|
31.0–106.0
|
25.0–244.0
|
35.50–185.0
|
H = 18.694*
|
< 0.001*
|
< 0.001*
|
< 0.001*
|
0.198
|
|
Mean ± SD.
|
60.25 ± 22.61
|
85.84 ± 49.38
|
85.12 ± 31.07
|
|
Median
|
55.0
|
70.0
|
79.0
|
|
AFP (ng/ml)
|
|
Min.–Max.
|
0.19–2.89
|
0.89–147.0
|
0.97–3.20
|
H = 39.139*
|
< 0.001*
|
< 0.001*
|
0.271
|
< 0.001*
|
|
Mean ± SD.
|
1.73 ± 0.57
|
5.20 ± 12.91
|
1.94 ± 0.62
|
|
Median
|
1.70
|
2.49
|
1.81
|
|
Platelet
|
|
Min.–Max.
|
182.0–441.0
|
36.0–401.0
|
118.0–359.0
|
F = 19.407*
|
< 0.001*
|
< 0.001*
|
0.020*
|
0.049*
|
|
Mean ± SD
|
290.86 ± 72.24
|
206.23 ± 92.15
|
242.13 ± 67.15
|
|
Median
|
278.0
|
210.0
|
253.0
|
- M mean, SD standard deviation, Min. minimum, Max. maximum, AST aspartate aminotransferase, ALT alanine aminotransferase, ALB albumin, TBIL total bilirubin, DBIL direct bilirubin, GGT gamma glutamyl transferase, ALP alkaline phosphatase, AFP alpha fetoprotein
- H: H for Kruskal-Wallis test, pairwise comparison between 2 groups was done using post hoc test (Dunn’s for multiple comparisons test), F: F for ANOVA test, pairwise comparison between 2 groups was done using post hoc test (Tukey). p: p value for comparing between the studied groups
- *Statistically significant at p < 0.05
