Skip to main content

Table 1 Comparison between the studied groups regarding biochemical data

From: The role of serum bile acid profile in differentiation between nonalcoholic fatty liver disease and chronic viral hepatitis

  Control (n = 51) Viral hepatitis (HBV + HCV) (n = 146) NAFLD (n = 39) Test of significance p Significance between groups
I vs. II I vs. III II vs. III
AST (IU/L)
Min.–Max. 10.0–44.0 10.0–143.0 13.0–55.0 H = 26.719 < 0.001* < 0.001* 0.001* 0.498
Mean ± SD 20.70 ± 6.55 40.60 ± 32.16 29.28 ± 11.50
Median 19.0 28.0 27.0
ALT (IU/L)
Min.–Max. 10.0–39.0 9.0–181.0 11.0–64.0 H = 17.105* < 0.001* < 0.001* < 0.001* 0.196
Mean ± SD. 20.25 ± 8.57 37.26 ± 35.63 31.90 ± 14.36
Median 18.0 24.50 31.0
ALB (g/dl)
Min.–Max. 4.0–4.80 1.40–5.50 2.80–4.80 F = 4.278* 0.015* 0.031* 0.024* 0.693
Mean ± SD. 4.42 ± 0.20 4.15 ± 0.78 4.06 ± 0.43
Median 4.40 4.40 4.13
TBIL (mg/dl)
Min.–Max. 0.23–1.27 0.20–7.30 0.23–1.20 H = 11.609* 0.003* 0.002* 0.499 0.042*
Mean ± SD. 0.51 ± 0.25 0.89 ± 1.10 0.52 ± 0.22
Median 0.40 0.56 0.50
DBIL (mg/dl)
Min.–Max. 0.10–0.70 0.10–6.10 0.10–0.70 H = 7.387* 0.025* 0.029* 0.922 0.037*
Mean ± SD. 0.23 ± 0.14 0.57 ± 1.08 0.22 ± 0.13
Median 0.20 0.23 0.20
GGT (IU/ml)
Min.–Max. 9.0–82.0 8.0–259.0 10.0–300.0 H = 25.195* < 0.001* < 0.001* < 0.001* 0.969
Mean ± SD. 22.91 ± 13.56 45.97 ± 44.15 44.78 ± 47.08
Median 19.0 32.0 29.0
ALP(IU/ml)
Min.–Max. 31.0–106.0 25.0–244.0 35.50–185.0 H = 18.694* < 0.001* < 0.001* < 0.001* 0.198
Mean ± SD. 60.25 ± 22.61 85.84 ± 49.38 85.12 ± 31.07
Median 55.0 70.0 79.0
AFP (ng/ml)
Min.–Max. 0.19–2.89 0.89–147.0 0.97–3.20 H = 39.139* < 0.001* < 0.001* 0.271 < 0.001*
Mean ± SD. 1.73 ± 0.57 5.20 ± 12.91 1.94 ± 0.62
Median 1.70 2.49 1.81
Platelet
Min.–Max. 182.0–441.0 36.0–401.0 118.0–359.0 F = 19.407* < 0.001* < 0.001* 0.020* 0.049*
Mean ± SD 290.86 ± 72.24 206.23 ± 92.15 242.13 ± 67.15
Median 278.0 210.0 253.0
  1. M mean, SD standard deviation, Min. minimum, Max. maximum, AST aspartate aminotransferase, ALT alanine aminotransferase, ALB albumin, TBIL total bilirubin, DBIL direct bilirubin, GGT gamma glutamyl transferase, ALP alkaline phosphatase, AFP alpha fetoprotein
  2. H: H for Kruskal-Wallis test, pairwise comparison between 2 groups was done using post hoc test (Dunn’s for multiple comparisons test), F: F for ANOVA test, pairwise comparison between 2 groups was done using post hoc test (Tukey). p: p value for comparing between the studied groups
  3. *Statistically significant at p < 0.05