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Egyptian Liver Journal

Table 1 Comparison between the studied groups regarding biochemical data

From: The role of serum bile acid profile in differentiation between nonalcoholic fatty liver disease and chronic viral hepatitis

 

Control (n = 51)

Viral hepatitis (HBV + HCV) (n = 146)

NAFLD (n = 39)

Test of significance

p

Significance between groups

I vs. II

I vs. III

II vs. III

AST (IU/L)

 Min.–Max.

10.0–44.0

10.0–143.0

13.0–55.0

H = 26.719

< 0.001*

< 0.001*

0.001*

0.498

 Mean ± SD

20.70 ± 6.55

40.60 ± 32.16

29.28 ± 11.50

 Median

19.0

28.0

27.0

ALT (IU/L)

 Min.–Max.

10.0–39.0

9.0–181.0

11.0–64.0

H = 17.105*

< 0.001*

< 0.001*

< 0.001*

0.196

 Mean ± SD.

20.25 ± 8.57

37.26 ± 35.63

31.90 ± 14.36

 Median

18.0

24.50

31.0

ALB (g/dl)

 Min.–Max.

4.0–4.80

1.40–5.50

2.80–4.80

F = 4.278*

0.015*

0.031*

0.024*

0.693

 Mean ± SD.

4.42 ± 0.20

4.15 ± 0.78

4.06 ± 0.43

 Median

4.40

4.40

4.13

TBIL (mg/dl)

 Min.–Max.

0.23–1.27

0.20–7.30

0.23–1.20

H = 11.609*

0.003*

0.002*

0.499

0.042*

 Mean ± SD.

0.51 ± 0.25

0.89 ± 1.10

0.52 ± 0.22

 Median

0.40

0.56

0.50

DBIL (mg/dl)

 Min.–Max.

0.10–0.70

0.10–6.10

0.10–0.70

H = 7.387*

0.025*

0.029*

0.922

0.037*

 Mean ± SD.

0.23 ± 0.14

0.57 ± 1.08

0.22 ± 0.13

 Median

0.20

0.23

0.20

GGT (IU/ml)

 Min.–Max.

9.0–82.0

8.0–259.0

10.0–300.0

H = 25.195*

< 0.001*

< 0.001*

< 0.001*

0.969

 Mean ± SD.

22.91 ± 13.56

45.97 ± 44.15

44.78 ± 47.08

 Median

19.0

32.0

29.0

ALP(IU/ml)

 Min.–Max.

31.0–106.0

25.0–244.0

35.50–185.0

H = 18.694*

< 0.001*

< 0.001*

< 0.001*

0.198

 Mean ± SD.

60.25 ± 22.61

85.84 ± 49.38

85.12 ± 31.07

 Median

55.0

70.0

79.0

AFP (ng/ml)

 Min.–Max.

0.19–2.89

0.89–147.0

0.97–3.20

H = 39.139*

< 0.001*

< 0.001*

0.271

< 0.001*

 Mean ± SD.

1.73 ± 0.57

5.20 ± 12.91

1.94 ± 0.62

 Median

1.70

2.49

1.81

Platelet

 Min.–Max.

182.0–441.0

36.0–401.0

118.0–359.0

F = 19.407*

< 0.001*

< 0.001*

0.020*

0.049*

 Mean ± SD

290.86 ± 72.24

206.23 ± 92.15

242.13 ± 67.15

 Median

278.0

210.0

253.0

  1. M mean, SD standard deviation, Min. minimum, Max. maximum, AST aspartate aminotransferase, ALT alanine aminotransferase, ALB albumin, TBIL total bilirubin, DBIL direct bilirubin, GGT gamma glutamyl transferase, ALP alkaline phosphatase, AFP alpha fetoprotein
  2. H: H for Kruskal-Wallis test, pairwise comparison between 2 groups was done using post hoc test (Dunn’s for multiple comparisons test), F: F for ANOVA test, pairwise comparison between 2 groups was done using post hoc test (Tukey). p: p value for comparing between the studied groups
  3. *Statistically significant at p < 0.05
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