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Table 2 Comparison of parameteric parameters of the three antiviral groups (p > 0.0)

From: Impact of different anti-HCV regimens on platelet count during treatment in Egyptian patients

 

Group

 

SIM/SOF

SOF/RBV

Triple

p value

Age (years)

55.05 ± 8.00

53.93 ± 9.27

53.55 ± 7.56

0.764

Weight (Kg)

81.73 ± 15.29

81.35 ± 12.41

80.05 ± 13.55

0.626

Height (m)

1.64 ± .08

1.66 ± .10

1.68 ± .09

0.092

BMI (Kg/m2)

30.36 ± 6.09

29.81 ± 4.39

28.40 ± 4.48

0.099

HCV positivity (years)

2.26 ± 2.81

6.67 ± 6.30 *

4.18 ± 5.85

< 0.001

Fib 4 calculation

5.10 ± 2.78

7.77 ± 3.79 *

3.74 ± 1.43 *#

< 0.001

Baseline platelets (*1000/mm3)

111.84 ± 40.35

77.18 ± 18.01 *

136.89 ± 31.70 *#

< 0.001

Baseline TLC (*1000/mm3)

4.89 ± 1.35

4.89 ± 1.52

5.97 ± 1.99 *#

0.002

Baseline ANC (*1000/mm3)

2.64 ± .95

2.59 ± 1.01

3.11 ± 1.27 *#

0.028

Baseline Hb (g/dl)

12.63 ± 1.38

12.97 ± 1.69

13.86 ± 1.58 *#

< 0.001

Baseline Alt (IU/l)

57.35 ± 39.05

64.52 ± 37.95

75.04 ± 58.82

0.198

Baseline Ast (IU/l)

65.58 ± 36.44

78.14 ±

42.81

72.91 ± 51.74

0.106

Baseline Bil T (mg/dl)

.99 ± .39

1.18 ± .57

.99 ± .69 #

0.024

Baseline Alb (g/dl)

3.50 ± .46

3.44 ± .46

3.95 ± .44 *#

< 0.001

Baseline PC (%)

79.38 ± 12.46

75.20 ± 13.93

81.98 ± 15.38 #

0.015

Baseline Creat (mg/dl)

.74 ± .20

.80 ± .19

.83 ± .23

0.088

Creat clearance (ml/min)

120.94 ± 33.11

116.76 ± 31.33

113.68 ± 30.77

0.663

Baseline HCV RNA by PCR (IU/ml)

949,173.30 ± 1195,220.29

1,051,988.49 ± 1,824,411.25

2,473,014.05 ± 6631,407.20

0.256

TSH (μIU/ml)

1.92 ± 1.46

1.97 ± 2.05

1.67 ± 1.20

0.518

Alpha fetoprotien (IU/l)

15.66 ± 22.75

28.92 ± 29.11 *

21.00 ± 30.15

0.001