Table 6 Association of HCC aggressiveness index with sociodemographic and clinical characteristics and genotype of HCC cases

Age/years, mean ± SD

54.64 ± 4.44

57.74 ± 4.98

56.18 ± 4.15

F = 2.66

P = 0.08

 Male

13 (59.1)

15 (65.2)

15 (53.6)

χ² = 0.708

P = 0.702

 Female

9 (40.9)

8 (34.8)

13 (46.4)

Albumin (g/dl), mean ± SD

3.36 ± 0.62

3.23 ± 0.71

3.28 ± 0.46

F = 0.280

P = 0.757

Bilirubin (mg/dl), median (IQR)

1.1 (0.90-1.7)

1.68 (0.80–2.4)

1.20 (0.825–1.5)

KW

P = 0.514

WBCS, mean ± SD

5.25 ± 1.89

4.40 ± 1.21

4.72 ± 2.28

F = 1.15

P = 0.32

HB (g/dl), mean ± SD

11.88 ± 1.43

10.91 ± 1.56

11.24 ± 1.84

F = 1.15

P = 0.32

Platelet ˟10³, mean ± SD

85.09 ± 29.89

116.09 ± 56.5

101.25 ± 38.8

F = 2.92

P = 0.061

ALT (u/l), median (IQR)

38.0 (27.0–43.0)

36.0 (32.0–55.0)

33.0 (29.25–65.75)

KW

P = 0.482

AFP (ng/dl), median (IQR)

190 (83.0–536.0)^a

83.0 (27.0–340.0)

67.0 (32.0–106.25)^a

KW

P = 0.013*

AST(u/l), median (IQR)

56.0 (47.0–88.0)

69.0 (66.0–89.0)

71.0 (53.0–98.0)

KW

P = 0.09

INR, mean ± SD

1.36 ± 0.13

1.41 ± 0.29

1.31 ± 0.15

F = 1.71

P = 0.189

DM, n (%)

8 (36.4)

9 (39.1)

14 (50.0)

P = 0.58

Hypertension, n (%)

6 (27.3)

6 (26.1)

7 (25.0)

P = 0.98

 TT/AA

2 (9.1)^a

6 (26.1)^b

21 (75.0)^a,b

MC

P < 0.001*

 CT/CA

8 (36.4)

9 (39.1)

4 (14.3)

 CC/CC

12 (54.5)

8 (34.8)

3 (10.7)

 GG

0 (0.0)^a,b

9 (39.1)^a,c

26 (92.9)^b,c

MC

P < 0.001*

 GA

12 (54.5)

8 (34.8)

2 (7.1)

 AA

10 (45.5)

6 (26.1)

0 (0.0)