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Table 3 Genotype distribution among the studied groups

From: Association of IL-10 and TNF-α polymorphisms with risk and aggressiveness of hepatocellular carcinoma in patients with HCV-related cirrhosis

  HCC, n = 73 (%) Cirrhotic, n = 85 (%) Test of significance Odds ratio (95% CI)
IL-10
 TT/AA 29 (39.7%) 16 (18.8%) χ2 = 8.2, P = 0.004*
χ2 = 0.35, P = 0.55
3.15 (1.42–6.99)
 CT/CA 21 (28.8%) 29 (34.1%) 1.26 (0.59–2.69)
 CC/CC 23 (31.5%) 40 (47.1%) Reference group
Hardy-Weinberg equation P = 0.002* P = 0.02*   
TNF-ɑ
 GG 35 (47.9%) 27 (31.8%) χ2 = 6.24, 2.67 (1.22–5.83)
 GA 22 (30.1%) 25 (29.4%) P = 0.01* 1.82 (0.79–4.15)
 AA 16 (21.9%) 33 (38.8%) χ2 = 2.01, P = 0.16 Reference group
Hardy-Weinberg equation P = 0.002* P = 0.001*   
  1. χ2 chi-square test
  2. *Statistically significant