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Table 2 Sociodemographic characteristics of the studied groups

From: Association of IL-10 and TNF-α polymorphisms with risk and aggressiveness of hepatocellular carcinoma in patients with HCV-related cirrhosis

 

HCC, n = 73

Cirrhotic, n = 85

Test of significance

Age/years, mean ± SD

56.21 ± 4.62

54.27 ± 7.63

t = 1.89

P = 0.06

Sex, N (%)

 Male

43 (58.9%)

39 (45.9%)

χ2 = 2.67

P = 0.102

 Female

30 (41.1%)

46 (54.1%)

DM, N (%)

31 (42.5%)

27 (31.8%)

χ2 = 1.94

P = 0.164

Hypertension, N (%)

19 (26.0%)

23 (27.1%)

χ2 = 0.021

P = 0.884

Albumin (gm/dl), mean ± SD

3.29 ± 0.59

3.56 ± 0.52

t = 2.98

P = 0.003*

Bilirubin (mg/dl), median (IQR)

1.2 (0.85–1.7)

1.2 (0.8–1.64)

z = 0.821

P = 0.412

WBCS, mean ± SD

4.78 ± 1.88

4.69 ± 1.85

t = 0.33

P = 0.739

HB (gm/dl), mean ± SD

11.33 ± 1.66

11.42 ± 1.53

t = 0.374

P = 0.709

Platelets ˣ 103, mean ± SD

101.05 ± 44.17

123.92 ± 36.76

t = 3.55

P = 0.001*

ALT (U/l), median (IQR)

35.0 (28.5–47.0)

35.0 (29.0–45.0)

z = 0.452

P = 0.65

AFP (ng/dl), median (IQR)

89.0 (33.0–230.5)

5.2 (2.8–9.7)

z = 9.98

P < 0.001*

AST(U/l), median (IQR)

68.0 (54.5–89.0)

40.0(36.0–47.0)

z = 7.67

P < 0.001*

INR, mean ± SD

1.36 ± 0.20

1.32 ± 0.19

t = 1.09

P = 0.275

  1. Parameters described as mean ± SD, median (interquartile range) or number (percentage)
  2. t Student t test, Z Mann-Whitney U test, χ2 chi-square test
  3. *Statistically significant