Skip to main content

Table 2 Association of vitamin D supplementation with different demographic, laboratory, and metabolic parameters of patients with NASH

From: Association of vitamin D supplementation with serum leptin and metabolic parameters in Egyptian patients with non-alcoholic steatohepatitis: a prospective study

Characteristics Before treatment After treatment t value p value Significance
Weight (kg) 106.3 ± 15.6 106.0 ± 15.9 0.0924 0.9266 NS
BMI (kg/m2) 35.7 ± 5.7 35.6 ± 5.7 0.0901 0.9284 NS
DBP (mmHg) 94.3 ± 11.9 91.5 ± 11.5 1.0553 0.2946 NS
HbA1c (%) 8.0 ± 2.4 6.8 ± 1.3 2.8558 0.0055 S
Hemoglobin (gm/dL) 13.5 ± 1.5 13.3 ± 1.2 0.6176 0.5386 NS
Platelet (× 103/μL) 288.5 ± 114.9 285.2 ± 98.3 0.1412 0.8881 NS
FBS (mg/dL) 165.6 ± 62.0 136.1 ± 32.7 2.6637 0.0094 S
Fasting insulin (μU/ml) 24.2 ± 3.0 22.9 ± 1.8 2.3090 0.0236 S
HOMA-IR 1.8 ± 0.7 1.4 ± 0.4 3.1134 0.0026 S
Creatinine (mg/dL) 0.9 ± 0.2 0.9 ± 0.3 0.2439 0.8080 NS
ALT (U/L) 78.2 ± 36.7 55.3 ± 21.3 3.4135 0.0010 S
AST (U/L) 108.6 ± 85.6 73.1 ± 54.2 2.2143 0.0297 S
Albumin (gm/dL) 3.8 ± 0.8 4.2 ± 0.7 2.2273 0.0288 S
NAFLD fibrosis score − 0.78 ± 0.9 − 0.9 ± 1.1 0.9934 0.3236 NS
TCHOL (mg/dL) 233.0 ± 40.9 226.5 ± 38.2 0.7431 0.4596 NS
LDL (mg/dL) 117.5 ± 41.6 129.8 ± 34.7 1.4286 0.1571 NS
HDL (mg/dL) 48.5 ± 7.59 48.1 ± 8.1 0.1858 0.8531 NS
Triglycerides (mg/dL) 229.7 ± 62.1 203.6 ± 49.8 2.0728 0.0415 S
ALP (mg/dL) 70.4 ± 7.3 63.7 ± 7.9 3.9422 0.0002 S
GGT (U/L) 43.3 ± 24.5 35.1 ± 8.7 2.0069 0.0482 S
Total bilirubin (mg/dL) 1.1 ± 0.4 1.1 ± 0.1 0.2267 0.8212 NS
Vitamin D (ng/ml) 15.6 ± 6.6 33.0 ± 7.6 11.0335 <0.0001 S
Leptin (ng/ml) 35.9 ± 28.4 23.5 ± 12.9 2.5129 0.0140 S