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Egyptian Liver Journal

Table 5 The liver tissue cAMP and CREB levels in control and NAFLD rats

From: The role of hepatic transcription factor cAMP response element-binding protein (CREB) during the development of experimental nonalcoholic fatty liver: a biochemical and histomorphometric study

Weeks

cAMP level (pg/mg liver protein)

CREB level (ng/mg liver protein)

Control

NAFLD

Control

NAFLD

2

4.08 ± 0.64

4.03 ± 1.16

0.76 ± 0.18

0.90 ± 0.20

4

3.59 ± 0.86

5.69 ± 0.74*#

0.84 ± 0.14

1.87 ± 0.36

6

4.20 ± 0.91

7.81 ± 2.05*#

0.75 ± 0.15

3.21 ± 0.72*#

8

3.95 ± 0.85

8.30 ± 1.13*#

0.95 ± 0.06

4.47 ± 0.80*#

10

4.65 ± 0.42

11.93 ± 1.83*#

0.88 ± 0.19

5.49 ± 0.62*#

12

3.91 ± 0.90

15.31 ± 1.51*#

0.79 ± 0.17

6.35 ± 0.63*#

14

4.25 ± 0.86

19.61 ± 1.63*#

0.82 ± 0.16

7.44 ± 0.59*#

  1. Data expressed as mean ± SE
  2. *Significant difference compared to control group at the same duration period by t test (P < 0.05)
  3. #Significant difference compared to the previous duration in the same group by paired t test (P < 0.05)
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