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Table 5 The liver tissue cAMP and CREB levels in control and NAFLD rats

From: The role of hepatic transcription factor cAMP response element-binding protein (CREB) during the development of experimental nonalcoholic fatty liver: a biochemical and histomorphometric study

Weeks cAMP level (pg/mg liver protein) CREB level (ng/mg liver protein)
Control NAFLD Control NAFLD
2 4.08 ± 0.64 4.03 ± 1.16 0.76 ± 0.18 0.90 ± 0.20
4 3.59 ± 0.86 5.69 ± 0.74*# 0.84 ± 0.14 1.87 ± 0.36
6 4.20 ± 0.91 7.81 ± 2.05*# 0.75 ± 0.15 3.21 ± 0.72*#
8 3.95 ± 0.85 8.30 ± 1.13*# 0.95 ± 0.06 4.47 ± 0.80*#
10 4.65 ± 0.42 11.93 ± 1.83*# 0.88 ± 0.19 5.49 ± 0.62*#
12 3.91 ± 0.90 15.31 ± 1.51*# 0.79 ± 0.17 6.35 ± 0.63*#
14 4.25 ± 0.86 19.61 ± 1.63*# 0.82 ± 0.16 7.44 ± 0.59*#
  1. Data expressed as mean ± SE
  2. *Significant difference compared to control group at the same duration period by t test (P < 0.05)
  3. #Significant difference compared to the previous duration in the same group by paired t test (P < 0.05)