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Table 4 The glucose homeostasis parameters of control and NAFLD groups

From: The role of hepatic transcription factor cAMP response element-binding protein (CREB) during the development of experimental nonalcoholic fatty liver: a biochemical and histomorphometric study

Weeks Fasting glucose Fasting insulin level Insulin resistance
Control NAFLD Control NAFLD Control NAFLD
2 73.2 ± 2.18 81.8 ± 3.07 0.70 ± 0.13 1.15 ± 0.23 0.12 ± 0.03 0.23 ± 0.04
4 72.4 ± 3.41 89.8 ± 3.35*# 0.90 ± 0.14 2.67 ± 0.16*# 0.15 ± 0.03 0.58 ± 0.02*#
6 77.2 ± 4.35 104.4 ± 5.15*# 0.95 ± 0.16 3.40 ± 0.20*# 0.17 ± 0.02 0.87 ± 0.02*#
8 74.8 ± 3.34 118.6 ± 4.08*# 0.86 ± 0.17 4.50 ± 0.39*# 0.15 ± 0.03 1.28 ± 0.06*#
10 76.6 ± 3.61 137.8 ± 3.56*# 0.76 ± 0.18 5.52 ± 0.38*# 0.14 ± 0.03 1.82 ± 0.07*#
12 80.4 ± 4.66 167.0 ± 3.26*# 0.90 ± 0.14 6.74 ± 0.39*# 0.17 ± 0.02 2.74 ± 0.12*#
14 80.6 ± 3.67 196.4 ± 5.81*# 0.94 ± 0.13 8.13 ± 0.37*# 0.18 ± 0.02 3.95 ± 0.11*#
  1. Data expressed as mean ± SE
  2. *Significant difference compared to control group at the same duration period by t test (P < 0.05)
  3. # Significant difference compared to the previous duration in the same group by paired t test (P < 0.05)