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Table 3 The serum lipid profile and hepatic lipid content of control and NAFLD groups

From: The role of hepatic transcription factor cAMP response element-binding protein (CREB) during the development of experimental nonalcoholic fatty liver: a biochemical and histomorphometric study

Weeks Serum triglycerides level Serum total cholesterol level Serum LDL level Serum HDL level Hepatic triglyceride content Hepatic cholesterol content
  Control NAFLD Control NAFLD Control NAFLD Control NAFLD Control NAFLD Control NAFLD
2 89.2 ± 3.83 221.4 ± 4.37* 76.4 ± 0.65 86.0 ± 2.90* 13.32 ± 1.01 39.12 ± 2.90* 45.74 ± 1.85 42.48 ± 1.57 41.2 ± 3.26 68.6 ± 6.68* 5.06 ± 7.51 85.0 ± 3.79*
4 102.7 ± 5.22 146.7 ± 6.55*# 76.0 ± 0.89 94.2 ± 2.63* 17.5 ± 2.25 56.90 ± 4.40*# 49.74 ± 1.66 37.04 ± 2.20*# 39.8 ± 2.75 81.6 ± 4.02*# 53.6 ± 8.16 98.0 ± 3.65*
6 108.6 ± 5.73 177.3 ± 8.39*# 81.0 ± 1.70 130.0 ± 2.86*# 24.22 ± 3.19 86.80 ± 6.44*# 48.68 ± 1.88 30.48 ± 1.58*# 42.6 ± 2.89 102.6 ± 3.72*# 52.2 ± 7.23 122.4 ± 4.59*#
8 95.1 ± 4.66 210.6 ± 10.71*# 85.8 ± 1.24 156.6 ± 4.40*# 29.96 ± 2.15 121.2 ± 3.23*# 49.6 ± 3.17 21.82 ± 1.80*# 41.0 ± 2.00 140.6 ± 4.69*# 58.6 ± 6.11 138.4 ± 5.97*#
10 106.2 ± 7.61 234.6 ± 8.62*# 91.8 ± 2.71 214.2 ± 5.28*# 32.18 ± 4.21 158.6 ± 4.94*# 51.52 ± 1.94 18.30 ± 1.77*# 44.8 ± 1.83 158.2 ± 4.86*# 62.8 ± 5.13 163.4 ± 5.80*#
12 109.7 ± 8.19 270.4 ± 10.6*# 98.2 ± 2.06 242.6 ± 3.83*# 31.40 ± 3.99 174.9 ± 3.79*# 51.86 ± 1.17 15.76 ± 1.42*# 50.4 ± 3.09 188.8 ± 262*# 65.6 ± 7.72 190.4 ± 5.47*#
14 111.5 ± 7.88 302.3 ± 11.47*# 108.2 ± 2.82 267.0 ± 2.07*# 37.48 ± 3.31 186.1 ± 4.28*# 51.02 ± 1.34 13.32 ± 1.55*# 57.2 ± 3.34 203.0 ± 4.57*# 69.2 ± 4.04 206.6 ± 4.25*#
  1. Data expressed as mean ± SE
  2. *Significant difference control group at the same duration period by t test (P < 0.05) compared to
  3. #Significant difference compared to the previous duration in the same group by paired t test (P < 0.05)