The role of hepatic transcription factor cAMP response element-binding protein (CREB) during the development of experimental nonalcoholic fatty liver: a biochemical and histomorphometric study

Egyptian Liver Journal

Table 3 The serum lipid profile and hepatic lipid content of control and NAFLD groups

Weeks	Serum triglycerides level		Serum total cholesterol level		Serum LDL level		Serum HDL level		Hepatic triglyceride content		Hepatic cholesterol content
	Control	NAFLD	Control	NAFLD	Control	NAFLD	Control	NAFLD	Control	NAFLD	Control	NAFLD
2	89.2 ± 3.83	221.4 ± 4.37*	76.4 ± 0.65	86.0 ± 2.90*	13.32 ± 1.01	39.12 ± 2.90*	45.74 ± 1.85	42.48 ± 1.57	41.2 ± 3.26	68.6 ± 6.68*	5.06 ± 7.51	85.0 ± 3.79*
4	102.7 ± 5.22	146.7 ± 6.55*#	76.0 ± 0.89	94.2 ± 2.63*	17.5 ± 2.25	56.90 ± 4.40*#	49.74 ± 1.66	37.04 ± 2.20*#	39.8 ± 2.75	81.6 ± 4.02*#	53.6 ± 8.16	98.0 ± 3.65*
6	108.6 ± 5.73	177.3 ± 8.39*#	81.0 ± 1.70	130.0 ± 2.86*#	24.22 ± 3.19	86.80 ± 6.44*#	48.68 ± 1.88	30.48 ± 1.58*#	42.6 ± 2.89	102.6 ± 3.72*#	52.2 ± 7.23	122.4 ± 4.59*#
8	95.1 ± 4.66	210.6 ± 10.71*#	85.8 ± 1.24	156.6 ± 4.40*#	29.96 ± 2.15	121.2 ± 3.23*#	49.6 ± 3.17	21.82 ± 1.80*#	41.0 ± 2.00	140.6 ± 4.69*#	58.6 ± 6.11	138.4 ± 5.97*#
10	106.2 ± 7.61	234.6 ± 8.62*#	91.8 ± 2.71	214.2 ± 5.28*#	32.18 ± 4.21	158.6 ± 4.94*#	51.52 ± 1.94	18.30 ± 1.77*#	44.8 ± 1.83	158.2 ± 4.86*#	62.8 ± 5.13	163.4 ± 5.80*#
12	109.7 ± 8.19	270.4 ± 10.6*#	98.2 ± 2.06	242.6 ± 3.83*#	31.40 ± 3.99	174.9 ± 3.79*#	51.86 ± 1.17	15.76 ± 1.42*#	50.4 ± 3.09	188.8 ± 262*#	65.6 ± 7.72	190.4 ± 5.47*#
14	111.5 ± 7.88	302.3 ± 11.47*#	108.2 ± 2.82	267.0 ± 2.07*#	37.48 ± 3.31	186.1 ± 4.28*#	51.02 ± 1.34	13.32 ± 1.55*#	57.2 ± 3.34	203.0 ± 4.57*#	69.2 ± 4.04	206.6 ± 4.25*#

Data expressed as mean ± SE
*Significant difference control group at the same duration period by t test (P < 0.05) compared to
#Significant difference compared to the previous duration in the same group by paired t test (P < 0.05)