Skip to main content

Table 1 Risk factors of gallstones and laboratory investigations among medical and surgical patients

From: Gallstones in Egyptian infants and children: risk factors, complications and outcome: a single center experience

 

Surgical, n = 7 (%)

Medical, n = 23 (%)

P value

Identified risk factors

5 (71.4)

19 (82.6)

0.6

Hemolytic anemia

   

Hereditary spherocytosis

1 (14.3)

1 (4.3)

0.4

Major thalassemia

0 (0)

1 (4.3)

1.0

G6PD deficiency

2 (28.6)

7 (30.4)

1.0

Dehydration

1 (14.3)

5 (21.7)

1.0

Therapy with ceftriaxone

2 (28.6)

4 (17.4)

0.6

Family history of gallstones

1 (14.3)

4 (17.4)

1.0

Hypertriglyceridemia

1 (14.3)

3 (16.7)

1.0

Cholestasis

0(0)

2 (8.7)

1.0

Prematurity

0 (0)

2 (8.7)

1.0

Cystic fibrosis

0 (0)

1(4.3)

1.0

Hemoglobin (g/dl) in mean ± SD

11.5 ± 0.95

11.7 ± 1.2

0.8

T. bilirubin (N < 1.5 mg/dl) median (IQR)

2.3 (1.1–5.1)

0.4 (0.2–0.8)

0.002*

D. bilirubin in median (IQR)

1.1 (0.5–3)

0.1 (0.05–0.2)

0.01*

ALT (N < 40 U/L) in median (IQR)

92 (32–178)

29 (20–45)

0.006*

AST (N < 60 U/L) in median (IQR)

55 (36–125)

37 (30–66)

0.1

GGT (N < 30 U/L) in median (IQR)

105 (36–114)

17 (11–64)

0.09

AP (N < 640 U/L) in median (IQR)

252 (180–533)

260 (192–371)

1.0

INR (N < 1.1) in mean ± SD

1.04 ± 0.04

1.1 ± 0.12

0.4

Cholesterol (N < 200 mg/dl) in mean ± SD

180 ± 47

134 ± 31

0.006*

HDL (mg/dl) in mean ± SD

38 ± 12

43 ± 9.5

0.3

LDL (mg/dl) in mean ± SD

120 ± 44

68 ± 29

0.002*

Triglyceride (N < 150 mg/dl) in median (IQR)

92 (62–115)

88 (62–119)

0.9

  1. *P value is significant
  2. ALT alanine aminotransferase, AP alkaline phosphatase, AST aspartate aminotransferase, D direct, GGT gammaglutamyl transpeptidase, G6PD Glucose-6-phosphate dehydrogenase, HDL high-density lipoproteins, INR international randomized ratio, IQR interquartile range, LDL low-density lipoproteins, RBCs red blood cells, SD standard deviation, T total