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Table 5 Agreement (sensitivity, specificity) to predict patients vs control

From: Role of circulating miRNA-17-3P as a potential diagnostic biomarker for sporadic colon cancer in Egyptian cohort

 AUCp95% CICutoffSensitivity (CI)Specificity (CI)PPV (CI)NPV (CI)
L.LU.L
miRNA0.996*< 0.001*0.9891.003> 1.61100 (100–100)96 (88.3–100)96.2(94–100)100 (100–100)
CA19.90.758*< 0.001*0.6500.866> 9.370.0(57.3–82.7)68.0 (49.7–86.3)81.4(69.7–93.0)53.1 (35.8–70.4)
CEA0.6280.0730.4910.765> 2.2956 (42.3–69.7)52 (32.4–71.5)70 (55.8–77.3)37.1 (43.4–65.9)
  1. AUC area under a curve, p value probability value, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
  2. *Statistically significant at p ≤ 0.05