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Table 5 Agreement (sensitivity, specificity) to predict patients vs control

From: Role of circulating miRNA-17-3P as a potential diagnostic biomarker for sporadic colon cancer in Egyptian cohort

 

AUC

p

95% CI

Cutoff

Sensitivity (CI)

Specificity (CI)

PPV (CI)

NPV (CI)

L.L

U.L

miRNA

0.996*

< 0.001*

0.989

1.003

> 1.61

100 (100–100)

96 (88.3–100)

96.2(94–100)

100 (100–100)

CA19.9

0.758*

< 0.001*

0.650

0.866

> 9.3

70.0(57.3–82.7)

68.0 (49.7–86.3)

81.4(69.7–93.0)

53.1 (35.8–70.4)

CEA

0.628

0.073

0.491

0.765

> 2.29

56 (42.3–69.7)

52 (32.4–71.5)

70 (55.8–77.3)

37.1 (43.4–65.9)

  1. AUC area under a curve, p value probability value, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
  2. *Statistically significant at p ≤ 0.05